Getting Started

Understanding the Data

Trials - a paginated table of clinical trials supported by the terminated awards. Click on the NCT ID for a pop up window that provides further detail, including the project summary and links to its full clinical trials record and its associated NIH award.

Trial filters include several protocol registration data elements (for a complete list of elements available on clinicaltrials.gov records please see this link).

• Study status reflects the overall recruitment status, which is one of the following:
• Not yet recruiting: Participants are not yet being recruited
• Recruiting: Participants are currently being recruited, whether or not any participants have yet been enrolled
• Enrolling by invitation: Participants are being (or will be) selected from a predetermined population
• Active, not recruiting: Study is continuing. Participants are receiving an intervention or being examined, but new participants are not being recruited or enrolled
• Completed: Participants are no longer receiving an intervention or being examined
• Suspended: Study halted prematurely but may resume
• Terminated: Study halted prematurely and will not resume; no further intervention or examinations of participants
• Withdrawn: Study stopped before any participants were enrolled
• Study type:
• Interventional: participants are prospectively assigned to an intervention to determine its effects on health or behavior
• Observational: participants are not assigned to an intervention; investigators monitor health outcomes as disease progresses, or observe the effects of interventions participants already receive as a part of routine health care.
• Sex: indicates whether trials are open to only one sex (assigned at birth) or both.

Awards - a paginated table of terminated awards imported from Grant Watch; we include a limited set of variables here. Click on an award number for a pop-up window that provides more details including the project abstract, a link to its file in NIH RePORTER, and any associated clinical trials. Award Filters allow you to narrow down the list of related clinical trials and an estimation of human subjects enrollment.

Awards may be filtered to narrow down the list of related clinical trials and an estimation of human subjects enrollment.

• Status - frozen funding, possibly reinstated, terminated, none; these categories are pulled directly from Grant Watch.
• The Institute Code, which indicates which of the ICs funded the award. This helps narrow awards by topic area.
• The funding category. NIH awards fall into one of nine categories- you can filter on these categories for broad results, or narrow down to activity code.
• The activity code. A three digit indicator of both the funding category and the specific activity supported within the funding category.
• Extensions, which indicate amendments and supplements. Included because many of the terminated awards were supplements for training scholars, like this one. In most cases, the parent award was not terminated.
• Organization, refers to the organization or foundation that received the award.
• Flagged Concepts: We've grouped these flagged words from Grant Watch into conceptual families for ease of filtering by concept. For more information regarding methods for categorizing concepts, please contact Amy Knopf. (asknopf@iu.edu)

Limitations

We can only link trials to awards when investigators include the NIH award number in their clinical trials record. Some awards have been active for 10+ years, and supported trials that have finished recruiting—you can filter them out by excluding trials with status=completed, or filter by projected completion date. The clinical trials records do not distinguish between currently enrolled human subjects and total planned enrollment. Therefore, our estimated total of research participants affected by award terminations includes both. We provide more explanation of limitations in this Google Doc.